Webanemia patients. As a result, RDW tends to be higher in iron deficiency anemia than in thalassemia minor(5). oBjECtivE This study is aimed at investigating the discriminatory power of RDW between iron deficiency anemia and thalassemia minor, with the diagnosis of alpha thalassemia trait being confirmed by molecular biology. WebIntroduction. β-Thalassemia is one of the hemoglobinopathies belonging to a class of genetic disorders. It occurs due to mutation in β-gene of autosomal chromosome 11. 1 The incidence of β-thalassemia trait in India is 3.3% with 1%–7% of couples being affected annually. 2 Approximately 300 mutations would occur in this type, affecting β-chain globin …
Importance of RDW value in differential diagnosis of ... - PubMed
Web. β-thalassemia minor or β-thalassemia trait refers to patients with a single defect in the β-globin gene, causing reduced expression of the beta chains. Patients are mildly anemic, hypochromic, and microcytic. The hallmark of β-thalassemia minor is an HbEP with an elevated HbA 2.As with the α-thalassemias, it is important to not inappropriately diagnose … WebBeta thalassemia major causes major problems and can result in early death. Complications may include delayed growth, bone problems causing facial changes, liver and gall bladder … dynamex retroactive
Alpha and Beta Thalassemia AAFP
WebThe RDW test is commonly used to help diagnose anemia, a condition in which your red blood cells can't carry enough oxygen to the rest of your body. The RDW test may also be used with other tests to help diagnose other conditions, including thalassemia, an inherited disease that can cause severe anemia. Why do I need an RDW test? WebIn a total group of 415 subjects (100 normal controls, 115 with iron deficiency anemia, 100 with the alpha-thalassemia trait, and 100 with the beta-thalassemia trait), the following indexes were analyzed: hemoglobin distribution width, red blood cell distribution width (RDW)-coefficient of variation, and RDW-SD. WebThalassemia major patients undergoing chronic transfusions and even thalassemia intermedia patients who may have only rare transfusions have an increased propensity to … crystal stone color chart