Phis-peg
WebbIn this study, pEGFP-LUC was used as a model plasmid and three distinct cationic lipids (dioleyloxy-propyl-trimethylammonium chloride [DOTMA], dioleoyl trimethylammonium propane [DOTAP], and cetylpyridinium chloride [CPC]) were tested along with PEG 5000, as a nonionic surfactant, to prepare glyceryl monostearate (GMS)-based cationic solid lipid … Webb5 jan. 2024 · Drug resistance is a crucial obstacle in chemotherapy that may lead to treatment failure and relapse in patients with cancer. 76 GA exhibits multi‑target anti‑cancer effects with few side effects, which shows the ability in reversing resistance to anti-cancer drugs in diverse cancer treatments.
Phis-peg
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Webb26 okt. 2024 · Synthesis of PEG-PHis-PSD (PHD) mPEG-COOH, NHS, and EDC were dissolved in anhydrous DMSO and allowed to react for 24 hours at room temperature. Then PSD or PHis-PSD were added into the mixture and further reacted for 2 days. Webb1 mars 2014 · The dual thermo- and pH-responsive properties of the PHis-PLGA-PEG-PLGA-PHis copolymers as well as their potential for the delivery of anticancer drugs have not been investigated to date. In addition, the copolymer featured a large proportion of hydrophobic blocks (PLGA and PHis) in its molecular structure, which could enable good …
Webb15 apr. 2015 · A dual functional nano-scaled drug carrier, comprising of a targeting ligand and pH sensitivity, has been made in order to increase the specificity and efficacy of the … WebbHerein, we design a simple strategy to fabricate poly (ethylene glycol) (PEG)-modified one-dimensional nanoscale coordination polymers (1D-NCPs) with intrinsic biodegradability, …
Webb24 okt. 2012 · Because further disruption of the micelle core forces ionized PHIS-PEG unimers to dissociate from the micelles, making micelles disintegrate and aggregate … Webb3 juli 2013 · Therefore, a polymeric nanocarrier based on PLGA- b -PEG carrying a double functionality of such kinds at its hydrophilic surface, and so enabling easy docking of diverse organic bioactive species and tracking agents, would represents a perfect support for theranostic purposes or drug delivery.
WebbA transformation system for the ringworm-producing dermatophyte Trichophyton mentagrophytes has been developed. The system employs the plasmid pHIS, which contains a bacterial hygromycin B phosphotransferase gene linked to Cochliobolus heterostrophus regulatory sequences (B. G. Turgeon, R. C. Garber, and O. C. Yoder, Mol. …
WebbPurpose: A new approach to monitor drug release and image inflammatory reactions in vitro and in vivo based on FRET mechanism was reported. Methods: In this study, mixed micelles containing a... notecard gps blueWebbThe AUC (0–∞), C max, and t 1/2 of the CUR-loaded micelles were increased by 2.07-fold, 3.14-fold, and 1.42-fold, respectively compared to CUR solution. 63 An endosomal micellar delivery system (F-pHSM-L61/CUR/Dox) consisting of a folate targeting ligand, poloxamer 407 (F127), and the pH-sensitive copolymer of PHis-PLA-PEG-PLA-Phis was used ... how to set personal development goals at workWebb4 nov. 2015 · In order to overcome drug resistant and enhance antitumor activity of DOX, a new pH-sensitive micelle (DOX/DQA-DOX@DSPE-hyd-PEG-AA) was prepared to simultaneously deliver DOX to nucleus and ... notecard cheat sheetWebbSuch Mn-ICG@pHis-PEG/GA under a mild NIR-triggered heating is able to induce effective apoptosis of tumor cells, realizing low-temperature PTT (~43 °C) with excellent tumor destruction efficacy. This work not only develops a facile approach to fabricate PEGylated 1D-NCPs with tumor-specific pH responsiveness and theranostic functionalities, ... notecard filters cigsWebbFor example, the mixed micelle system composed of PHis-PEG and folate conjugated PLLA-PEG showed high cytotoxicity against MDR cells after folate mediated endocytosis.20,21 Later, the mixed micelles constructed from DSPE-PEG(2K), DSPE-PEG(3.4K)-2C5, and PHis-PEG(2K) were developed.22 To sum up, various PHis based … notecard file holdersWebb29 sep. 2024 · Aim: To carboxylate kraft lignin towards the functionalization of carboxylated lignin nanoparticles (CLNPs) with a block copolymer made of poly (ethylene glycol) (PEG), poly (histidine)... notecard exampleWebbvia a one-step method. After loading gambogic acid (GA), such Mn-ICG@pHis-PEG/ Owing to the GA-induced down-regulation of Hsp90 to overcome the thermal-resist-ance of tumor cells, highly effective in vivo destruction of tumors is relized with Mn-ICG@pHis-PEG/GA under low-temperature photothermal therapy at 43 °C. how to set personal goals in life