WebAug 9, 2024 · This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy. WebCircTHBS1 facilitated the malignant behavior and epithelial-to-mesenchymal transition of GC cells. Mechanistically, circTHBS1 sponged miR-204-5p to promote the expression of Inhibin Subunit Beta A (INHBA). Moreover, circTHBS1 could enhance the HuR-mediated mRNA stability of INHBA, which subsequently activated the TGF-β pathway. ...
CircTHBS1 drives gastric cancer progression by increasing INHBA …
WebMar 1, 2024 · CircTHBS1 drives gastric cancer progression by increasing INHBA mRNA expression and stability in a ceRNA- and RBP-dependent manner Shengkui Qiu, Bowen Li, +18 authors Zekuan Xu Published 1 March 2024 Biology Cell Death & Disease Circular RNAs (circRNAs) play vital regulatory roles in the progression of multiple cancers. WebCirc THBS1 promoted IC cell proliferation, migration, EMT process, and inflammation by regulating the miR‐139‐5p/MFN2 axis indicating that circTHBS1 might be a potential target for IC treatment. Circular RNA (circRNA) have been found to play an important role in the progression of many diseases, including interstitial cystitis (IC). However, the role of … how many inmates suffer from mental illness
Figure 6. miR-139-5p suppresses tumor growth in vivo. (A)...
WebDownload scientific diagram miR-139-5p inhibits A549 non-small cell lung cancer colony formation, migration and invasion by suppressing expression of HDGF. (A) Colony formation ability in A549 ... WebMar 21, 2024 · Entrez Gene Summary for MIR211 Gene. microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and … Webtransfection with small interfering (Si)-CircTHBS1, but it was enhanced remarkably after transfection with CircTH-BS1-overexpression vector (OE). There were complementary sites in circTHBS1 for the 3'-UTR of miR-129-5p, and the fluorescence intensity of wild-type circTHBS1 declined evidently after interacting with miR-129-5p. Besides, there howard hanna burton ohio